VERIFICATION OF BLOOD-BRAIN BARRIER DISRUPTION BASED ON THE CLINICAL VALIDATION PLATFORM USING A RAT MODEL WITH HUMAN SKULL

Verification of Blood-Brain Barrier Disruption Based on the Clinical Validation Platform Using a Rat Model with Human Skull

Methods to improve drug delivery efficiency through blood-brain barrier disruption (BBBD) based on microbubbles and focused ultrasound (FUS) are continuously being studied.However, most studies are being conducted in preclinical trial environments using small animals.The use of the human skull shows differences between the clinical and preclinical

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Hyperacute assessment of vertigo in suspected stroke

The management of patients with acute vertigo is most challenging in the hyperacute phase, both due to the complexity of vertigo as a symptom, the range of possible causes, and the lack of training in neuro-otology for non-specialists.Perhaps of greatest relevance is differentiating between peripheral (usually benign, e.g., inner ear) causes and ce

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